The Wii/PC version of the game follows the film's storyline and expands it in some respects. Alice, helped by friends like the Mad Hatter and Cheshire Cat, must battle the Queen and save Wonderland. It's said to incorporate an "upgradeable combat system" and numerous unlockables to encourage replayability.
DS and mobile phone versions are also planned, though they obviously won't look quite so fancy. The Wii, PC, and DS will receive the game in March 2010 and the mobile game is due in February. If you want to ogle a slightly larger version of the screenshot, head over to Kotaku.
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