Amid the many projects he signed on to in his post-Hangover career boom, Ed Helms has Cedar Rapids, a road trip comedy about a Wisconsin insurance salesman whose mind is blown by the big-city experience at a work conference in Cedar Rapids, Iowa. While Helms has perfected the big-fish-in-small-pond vibe as Andy on The Office, there's really one master at capturing the befuddled everyman-- John C. Reilly.

Luckily, they've brought him on board as well. THR reports that Reilly will play a fellow conference attendee, a family man treating the conference as his own personal vacation. Miguel Arteta, who has Youth in Revolt coming out in January, will direct, with Alexander Payne, Jim Taylor and Jim Burke producing.