While it is hard to believe, eight years have passed since Katherine Heigl left her role as Dr. Izzie Stevens on Grey's Anatomy. Nearly a decade later, a lot has changed on the medical drama, particularly within the cast of characters' love lives. That includes Izzie's ex Dr. Alex Karev, who recently fully moved on from Izzie and married Jo. So how did Heigl react to that news? Here is what the former Grey's Anatomy actress had to say:

Oh my God! Well, that's exciting. Alex needed to find love --- true love. I don't know [how Izzie would react]. I'd have to start wondering where Izzie is. Like, what is she doing? Where did she go? I would hope that she pursued her [medical] career. She could have children by now. She could be married. . . . If she has moved on, then I would expect Izzie to be very happy for him. She would want him to be happy.

Suffice it to say, Katherine Heigl was not so distraught by the revelation when speaking with TV Line, either from her own p.o.v. or from Izzie's. Izzie and fellow former show leads George and Christina were referenced in Grey's Anatomy's 300th episode, proving the show can still acknowledge her absence even as it marries off her ex. Given how many bad things typically transpire on Grey's Anatomy within regards to its characters' happiness, it is amazing that there was actual good news to share from the actress, who seemed happy to ponder about Izzie's life for a bit.

The question of where Izzie has ended up has undoubtedly popped up throughout the years, and it's not just a fan thing. Her portrayer Katherine Heigl is still able to go into "Izzie-mode" nearly a decade after leaving the role behind to put some thought into where the character would be. So while we know Heigl's perspective Alex's marriage to Jo from the perspective of Izzie also being married, how does she think Izzie would react to the pair's marriage if Izzie were single? Heigl weighed in with a brief assessment that went to the core of the matter, saying:

She'd be jealous for sure, right? She'd want him to hold out for her.

Katherine Heigl's observation is arguably a pretty accurate estimation of Izzie's point of view. When you play a character for six seasons, it stands to reason that you would have a good grasp on where they might stand on an issue, especially one dealing with past relationships. Izzie and Alex had their highs and lows during their run on Grey's Anatomy. So one would hope they would both be happy for each other, even though did not end up finding said happiness together. After all, sometimes those are the necessary endings life ends up having.

While Heigl is curious to know how Izzie would be faring today, fans may not ever learn the answer via an actual on-screen return to the role. After leaving the show that helped make her a household name, Heigl had previously expressed some interest in returning to the series to resolve the status of Izzie's life, but it's not a return that fans should count on, considering the manner in which she left.

Grey's Anatomy returns for its fifteenth season this fall on ABC. You can catch Katherine Heigl on Suits when Season 8 begins July 18 on USA. For other television shows set to arrive this summer, check out CinemaBlend's guide to TV's summer premieres.

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