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The title Jay and Seth vs. The Apocalypse has been floating around since June 2007, when it was a joke trailer starring Seth Rogen and Jay Baruchel, who at the time were starring together in Judd Apatow's Knocked Up. A year later word got out that they were making an actual movie about it, starring Rogen and Baruchel as the last survivors of the apocalypse who couldn't help but get on each others' nerves.
But that started to seem like the product of the 2007-era Apatow bubble, when the writer-director-producer seemed able to shepherd any actor or project to success; in 2010, a year after Funny People was a severe box office disappointment, Baruchel made the kind of vague promise about it still happening that doesn't usually bode well. But with Rogen about to star in 50/50, a movie he produced and also stars in, he revealed to Movies.com that production on Jay and Seth vs. The Apocalypse is actually set to begin in February.
Rogen and Evan Goldberg, who co-produced 50/50 together and of course co-wrote Superbad too, will be moving on as co-directors on Jay and Seth; you can't help but imagine the two lifelong friends might find themselves squabbling like the guys in the trailer, and surely that'll come up on the publicity rounds eventually. Rogen also calls the move "oddly personal," maybe thanks to his real-life friendships with both Baruchel and Goldberg, and also hints at a much bigger cast than we saw in the "teaser": "It's now much more than just Jay and Seth -- there's many other people vs. the apocalypse now. It's gonna be crazy."
Here's the original short video if you missed it the first time around. Both Baruchel and Rogen seem to have gotten over that bump of seeming entirely too overexposed, and Jay and Seth is seeming like an actual good idea again for the first time in a few years.