A film adaptation about a beloved Great Dane deserves a great cast and 20th Century Fox has been compiling such a group right under our noses. We’ve heard that the live action/CG-animated film based on Brad Anderson’s comic strip Marmaduke would feature Judy Greer as Debbie Winslow and Lee Pace as Phil Winslow, but Coming Soon has dug up the details on the rest of the cast and it’s pretty impressive.

Here it goes: Amanda Seyfried voices Mazie, Jeremy Piven is Bosco, Ron Perlman is Chupadogra, Christopher Mintz-Plasse is Guiseppe, Stacy ‘Fergie’ Ferguson is Jezebel, Steve Coogan is Raisin, George Lopez is Carlos and Damon Wayans Jr. is Thunder.

Yes, the cast is terrific but don’t get ahead of yourself. A star-studded voice cast doesn’t always mean a hit. Does anyone remember Battle for Terra? Probably not because the film only pulled in just over $1.5 million at the domestic box office even though it boasted big names like Evan Rachel Wood, Brian Cox, Luke Wilson, Justin Long, Amanda Peet, Dennis Quaid, Chris Evans and James Garner. On the other hand the live action animation mix could push Marmaduke in the direction of hits like Garfield/ and Alvin and the Chipmunks, both of which garnered sequels.

Director Tom Dey shot the film this summer in Vancouver and it is set to hit theaters on June 4th, 2010.

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