32 Actors Who Have Starred In Multiple HBO Shows

HBO doesn't have a monopoly on prestige television, but they are the king of it. The network loves to work with the same people who have proved they have what it takes to make great shows. That includes many of the same great actors who appear on more than one show. Some of these actors have appeared in three or four (or more) shows over the years, but for this list, we're sticking with at least two, usually the ones they are best known for. Actors like Wendell Pierce, Cynthia Nixon, and many more.

Wendell Pierce - The Wire And Treme

Wendell Pierce first broke out as the best-dressed detective in the Baltimore Homicide Unit on The Wire. Pierce's character, Bunk Moreland, appears in every episode of the show. A couple of years after The Wire ended in 2008, the show's creator returned to HBO with Treme, and it was a natural fit to include Pierce, who is a New Orleans native, in the cast.

Carrie Coon - The Gilded Age And The White Lotus

2025 was a huge year for Carrie Coon on HBO. Not only did she return for Season 3 of The Gilded Age as the determined high society lady, Bertha Russell, but she also killed it on the third season of the anthology series The White Lotus. She stole the show with her monologue in the final episode of that show, while continuing to dominate New York society in the 1880s in The Gilded Age.

Steve Buscemi - The Wire And Boardwalk Empire

Steve Buscemi's first appearance on HBO came when he joined the cast of The Sopranos as Tony Blundetto, Tony Soprano's cousin, in Season 5 of the legendary peak TV-era show. He wasn't on the show long, but a couple of years later, he played a much bigger role on Boardwalk Empire. He played the fictional mob boss Nucky Thompson in the period piece created by Sopranos writer Terrance Winter.

Evan Rachel Wood - True Blood And Westworld

Evan Rachel Wood started her career as a talented child actor and made her first appearance on HBO as a recurring character in True Blood. She made an even bigger splash on the network as one of the main characters in Westworld. Wood also appeared in the miniseries Mildred Pierce on HBO.

Alexander Skarsgård - True Blood And Big Little Lies

Alexander Skarsgård is a true HBO regular. His first show for the network, the limited series Generation Kill, aired in 2008 and he returned to the network that same year as a series regular in the vampire hit True Blood. While still starring on that show, he made a one-off appearance in the series finale of Eastbound and Down. He was a main cast member on Big Little Lies, playing a very dark character (and earning an Emmy in the process), before he took on a notable guest-starring role in Succession, earning two more Emmy nominations.

Sydney Sweeney - Euphoria And The White Lotus

Sydney Sweeney burst onto the scene alongside her castmates in the teen drama Euphoria on HBO in 2019 and in 2022, she also appeared in Season 1 of The White Lotus. She earned not one, but two Emmy nominations that year, one for each show.

Edie Falco - Oz And The Sopranos

The HBO show Oz was an early entry in the "peak TV era" from the network, running for six seasons in the late 1990s and early 2000s. The cast of Oz was stacked and included Edie Falco as Officer Diane Whittlesey. That isn't the show she is most famous for on the network, of course. As Falco's time was coming to a close, she landed the role of a lifetime as Carmela Soprano in The Sopranos, and her amazing performances earned her three Emmy awards.

Aidan Gillen - Game Of Thrones And The Wire

Petyr "Littlefinger" Baelish in Game of Thrones is one of the great TV villains of all time, and the character was played brilliantly by Aidan Gillen. It wasn't Gillen's first major role on HBO, as that came a few years earlier when he played the ambitious politician Tommy Carcetti on the final three seasons of The Wire.

Cynthia Nixon - And Just Like That And The Gilded Age

itsCynthia Nixon has been a staple on HBO for decades now, starring as Miranda Hobbes in And Just Like That... and it's predecessor. She's also one of the stars of the incredible period drama The Gilded Age as the spinster-turned-wealthy widow Ada Forte, née Brook.

Michiel Huisman - Game Of Thrones And Treme

Treme, which ran for four seasons on HBO, had a whole host of actors who were HBO regulars. Michiel Huisman, who played the musician only known as "Sonny" on the New Orleans-based show, was also starring in a little show called Game of Thrones at the same time on the network, playing Daario Naharis.

Michelle Monaghan - True Detective And The White Lotus

It must be incredibly rewarding for any actor to have the opportunity to star in two anthology shows on HBO. Michelle Monaghan knows exactly how it feels. She first starred in Season 1 of True Detective and, more recently, was part of the stellar cast of Season 3 of The White Lotus.

Michael K. Williams - The Wire And Boardwalk Empire

The late Michael K. Williams left behind an incredible legacy at HBO. He was, of course, one of the most incredible TV characters of all time as Omar Little on The Wire, and he followed that up with a great turn as a gangster in 1920s New Jersey in Boardwalk Empire. Those weren't his only appearances on the network. He popped up in a one-off scene on The Sopranos in 2001, then later in the miniseries The Night Of. His final television credit before his tragic death was on the HBO show Lovecraft Country.

Alexandra Daddario - The White Lotus And True Detective

Before earning an Emmy nomination for her great turn as newlywed Rachel Patton in Season 1 of The White Lotus, Alexandra Daddario had a recurring role on another HBO anthology series, True Detective, during its first season. She even had a cameo early in her career in The Sopranos.

Murray Bartlett - The White Lotus And The Last Of Us

It's easy to see why The White Lotus was such a monster hit when it aired its first season, with Murray Bartlett stealing the show as the hotel manager who gets caught in a serious downward spiral as the show goes on. He's hilarious and heartbreaking at the same time. Later, he was cast in "Long, Long Time," one of the most beloved episodes of The Last of Us, as Frank, the deceased lover of Bill, played by Nick Offerman. While it was only one episode, it was so good that we had to include it here. Bartlett was also a regular cast member on the HBO show Looking.

Danny McBride - Eastbound And Down And The Righteous Gemstones

What is there to be said about Danny McBride's various sitcoms on HBO? After making his name in supporting roles in movies like Pineapple Express and Tropic Thunder, he arrived on HBO in the now-legendary Eastbound and Down. His next hit for the network was Vice Principals alongside Walton Goggins, and then as Jesse Gemstone on The Righteous Gemstones.

Clarke Peters - The Wire And Treme

It's hard to believe that The Wire is one of those shows that never won an Emmy. That goes double for the excellent cast, including the great Clarke Peters, who played Lester Freamon in all five seasons of the show. Like some of his co-stars on the show, he also appeared in Treme on HBO.

Jeanne Tripplehorn - The Gilded Age And Big Love

Jeanne Tripplehorn is a veteran actor whose career stretches back to 1992's Basic Instinct. She was a big part of Big Love on HBO as Bill's only legal wife in the show about polygamy in Utah. Tripplehorn also starred in a recurring role on The Gilded Age as a disgraced high society outcast who happens to be one of the kindest characters on the show. She was also nominated for an Emmy for her role as Jacqueline Kennedy Onassis in Grey Gardens on HBO.

Jeffrey Wright - Westworld And Boardwalk Empire

Jeffrey Wright is one of the best actors of his generation, and he's had an opportunity to show off just how great he is in multiple HBO shows. First, he won an Emmy for his role in the miniseries Angels in America. Later, he had a recurring role on Boardwalk Empire, before his fantastic turn on Westworld, for which he was nominated for three more Emmys, but sadly didn't win one. In 2025, he reprised his voice role in The Last of Us video game in the HBO adaptation.

Jamie-Lynn Sigler - The Sopranos And Entourage

Jamie-Lynn Sigler occupies an interesting spot here. Of course, she's best known for her role as Meadow Soprano on The Sopranos. Her next role on HBO came in a role that was a fictionalized version of herself dating Turtle in Entourage.

Walton Goggins - Vice Principals And The White Lotus

Walton Goggins has been one of the hardest-working actors in Hollywood for many years, and in 2025, he really upped his profile with his fantastic performance in Season 3 of The White Lotus. It was his third major show on HBO after Vice Principals and The Righteous Gemstones.

Lena Headey - Game Of Thrones And The White House Plumbers

She played one of the greatest villains of all time on Game of Thrones, and Lena Headey returned to HBO in 2023 in the underrated miniseries The White House Plumbers, where she played Dorothy Hunt, wife of one of the Watergate burglars, E. Howard Hunt.

Pedro Pascal - Game Of Thrones And The Last Of Us

Like a lot of actors, Pedro Pascal put in a ton of work early in his career with one-off roles in every show you can imagine. Then, in 2014, he was cast as Oberyn Martell on Game of Thrones, and his career blew up. More recently, he's been breaking hearts on The Last of Us on HBO.

Indira Varma - Game Of Thrones And Rome

The Game of Thrones cast was absolutely stacked, including the great Indira Varma, who played Ellaria Sand in 13 episodes of the show. That wasn't her first time in an HBO show, however. In 2005, she starred as Niobe in two seasons of Rome, the incredibly underrated (and expensive to produce) historical drama created by John Milius.

Jim True-Frost - The Wire And Treme

Jim True-Frost's character in The Wire has one of the most interesting character arcs on a show full of great arcs. His performance as Roland Pryzbylewski was, like so many others on the show, nothing short of excellent. Like others on The Wire, True-Frost also starred in Treme. He even had a cameo in Boardwalk Empire as legendary lawman Eliot Ness.

Kim Dickens - Deadwood And Treme

Kim Dickens has a stellar television resume, and two jewels on that CV are both HBO shows. First, she was one of the main characters, Joanie, in Deadwood. Later, she starred on Treme.

John Hawkes - Deadwood And Eastbound And Down

The original cast of Deadwood was a bunch of heavyweights, including John Hawkes, who played Sol throughout the run of the show. A few years later, the versatile actor returned to HBO in a completely different kind of role as the brother of Kenny Powers in Eastbound & Down. Most recently, he put in a fantastic performance in Season 4 of the anthology series True Detective.

Rose Leslie - Game Of Thrones And The Time Traveler's Wife

The Time Traveler's Wife is one of the more under-the-radar shows in HBO history. Rose Leslie led the cast of the show that was canceled after one season, despite a passionate fanbase. Of course, Leslie first became a star on HBO as Ygritte on Game of Thrones.

Bobby Cannavale - Boardwalk Empire And Vinyl

Bobby Cannavale really made his name on HBO as the volatile gangster Gyp Rosetti in Boardwalk Empire, though his first gig on the network was in a small role on Six Feet Under. After Boardwalk Empire, he teamed up with the creators of Vinyl, starring in the lone season of the short-lived show.

Edi Patterson - The Righteous Gemstones And Vice Principals

The Righteous Gemstones and Vice Principals are two shows that were perfect for Edi Patterson. She's wonderful at playing quirky characters, fitting in great with the cast of both of those shows.

Domenick Lombardozzi - The Wire And Boardwalk Empire

Herc in The Wire is an obnoxious character that is hard to love, but Domenick Lombardozzi's performance charms everyone who watches the show. He repeated the feat later on Boardwalk Empire.

Regina King - Watchmen And The Leftovers

If anyone on this list needs no introduction, it's the great Regina King. She is a force of nature in everything she does, including two excellent HBO shows, The Leftovers and the one-and-done Season of Watchmen.

Michael Imperioli - The Sopranos And The White Lotus

Some people might remember Michael Imperioli as Spider in Goodfellas, but most will first know him as Christopher Moltisanti, Tony's frustrating nephew in The Sopranos. He returned to HBO in Season 2 of The White Lotus and once again reminded fans of the network how great he can be.